Multicenter Clinical Trial of Deep Brain Stimulation in Early Stage Parkinson’s Disease

Deep brain stimulation (DBS) is an effective treatment for many patients with advanced stage Parkinson’s disease (PD) when symptoms are not adequately controlled with medication. Vanderbilt University recently completed a U.S. Food and Drug Administration (FDA)-approved pilot clinical trial of safety and tolerability of DBS in early-stage PD. Based on the results of the pilot, the FDA approved Vanderbilt University to conduct a large-scale, multicenter clinical trial evaluating the safety and efficacy of DBS in very early stage Parkinson’s disease.

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